So I did at one time run a ftf Traveller game with a bunch of friends.

One moved away and the group lost and added and we did different games and
different DM's

The friend is coming back for a visit, so it was decided to surprise him
with a one shot Traveller game.

I was thinking I would start them in a asylum, characters are inmates with
restricted memory and drugs that hamper physical and mental abilities.

Two questions:

Anyone deal with psychotropics affecting a characters abilities, gumption
or self motivation?

I was thinking the drugs would lower stats without character knowledge,
('I hit him with a chair, I have a 9 STR.'  GM thinks "OK, he has a 4 str
because of the drugs)

Also to affect motivation you would have to roll a 1 on a six sided dice
to to do something dangerous.

Anyone ever do anything like this?

Was thinking that the characters don't know their background, skills etc.

Also looking for ideas for the reason the group is in the asylum.
Everyone has a piece of the puzzle.

Ideas?

Thanks

Eric