In terms of social development, I wonder how frequently the common knowledge of typical things about the Imperium gets lost. A small colony sets up (perhaps without informing the imperial government, or outside the domain of the Imperium) via contracted transport
of the colonists to a world and after a few curious free trader visits there are no more. The colony is more or less on its own. Children born to that colony will probably be taught that there is a huge empire out there among the stars that they came from,
but none of them are likely to ever visit it and they won't be able to relate that first hand experience to their own children. Teaching might shift to more practical matters ("make sure to get the harvest in before aphelion") and most of the concept of the
Imperium gets lost completely. There's not really that connection to stabilize social development and I imagine that the colony will rapidly (a couple of generations in) develop its own culture and view of the universe.